Niveles mayores de inflamación del sistema nervioso en personas con síndrome de fatiga crónica

Mediante el uso de tomografía por emisión de positrones, unos científicos han comprobado que los niveles de neuroinflamación, o inflamación del sistema nervioso, son más altos en pacientes con el síndrome de fatiga crónica que en personas sanas.

Dicho síndrome es una enfermedad incapacitante caracterizada por una fatiga crónica, profunda e inhabilitante. Por desgracia, no se comprenden bien sus causas.

La idea de que la inflamación de las células nerviosas puede ser una causa de la enfermedad no es nueva, pero desde que se propuso por vez primera ha carecido de evidencias claras que la respalden. Ahora, la situación puede que cambie de manera sustancial, ya que en este nuevo estudio, clínicamente importante, unos investigadores del Instituto RIKEN, la Universidad de la Ciudad de Osaka, y la Universidad Kansai de Ciencias del Bienestar, todas estas entidades en Japón, han encontrado que efectivamente los niveles de los marcadores de neuroinflamación son altos en los pacientes con síndrome de fatiga crónica, en comparación con los sujetos sanos del grupo de control.

Los autores del estudio también hallaron elevada la inflamación en ciertas áreas del cerebro, concretamente la corteza cingulada, el hipocampo, la amígdala, el tálamo, el mesencéfalo y el puente troncoencefálico, de una manera que se correlacionaba con los síntomas, de tal modo que, por ejemplo, los pacientes que tenían la cognición deteriorada tendían a mostrar neuroinflamación en la amígdala, que se sabe está implicada en las funciones cognitivas. Esto proporciona pruebas claras de la asociación entre la neuroinflamación y los síntomas experimentados por pacientes con síndrome de fatiga crónica.
Mediciones de neuroinflamación en pacientes con el síndrome de fatiga crónica. (Imagen: RIKEN)

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La investigación realizada por el equipo del Dr. Yasuyoshi Watanabe, del Instituto RIKEN, podría llevar a una mejor diagnosis y finalmente al desarrollo de nuevas terapias para proporcionar alivio a las muchas personas de todo el mundo que se ven afectadas por esta enfermedad.

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March of Dimes celebra la derrota de la Polio y la misión actual sobre la salud de los bebés

Moneda de la March of Dimes celebra la derrota de la polio y la misión actual sobre la salud de los bebés Moneda de la March of Dimes celebra la derrota de la polio y la misión actual sobre la salud de los bebés FDR y el doctor Jonas Salk en el nuevo dólar de plata de la Casa de la Moneda de los Estados Unidos PR Newswire. WEST POINT, Nueva York, 11 de marzo de 2015 /PRNewswire-HISPANIC PR WIRE/

— El legado de la March of Dimes, desde vencer la polio hasta luchar por la salud de los bebés, se celebra en una nueva moneda conmemorativa de 2015, acuñada hoy en honor de los logros de la organización, que durante más de 75 años ha mejorado la vida de la gente.
La moneda de plata de un dólar, autorizada por el Congreso, combina el pasado, el presente y el futuro de la March of Dimes. Muestra a un presidente y a un científico, Franklin D. Roosevelt y el doctor Jonas Salk, que tuvieron un papel fundamental en el esfuerzo de la March of Dimes por derrotar la polio, en el anverso de la moneda. El reverso de la moneda tiene la imagen de un bebé acunado en la mano de su padre, un símbolo de la misión actual de la March of Dimes de ayudar a cada uno de los 4 millones de bebés nacidos en los Estados Unidos cada año a tener un principio saludable en la vida.
Aidan Lamothe, de siete años de edad y de Manchester, Nuevo Hampshire, que nació 11 semanas prematuro, se unió a la presidenta de la March of Dimes, la doctora Jennifer L. Howse; a Peter L. Salk, MD, el hijo mayor del doctor Jonas Salk y presidente de la Jonas Salk Legacy Foundation, y a la tesorera de los Estados Unidos, Rosie Ríos, para acuñar hoy la moneda en la Casa de la Moneda de los Estados Unidos en West Point.

“La visión y el liderazgo de FDR y del doctor Jonas Salk impulsaron el movimiento hacia un mundo que ahora está casi libre de la polio”, dijo la doctora Howse. “Estamos encantados de que el Congreso y la secretaria del Tesoro hayan reconocido este logro –así como nuestra labor actual– con el Dólar de Plata de la March of Dimes de 2015″.
“La lucha contra la polio ha sido un esfuerzo colectivo que ha abarcado las contribuciones de millones de individuos en todo el mundo”, dijo el doctor Salk. “Esta moneda es un tributo a la March of Dimes y al legado de mi padre, y rinde homenaje a todos los que se esfuerzan por mejorar la salud de los bebés y de los niños en todas partes. Es especialmente relevante que esta moneda se acuñe en el centenario del nacimiento de mi padre”.

“Estoy emocionada al estar aquí hoy para rendir homenaje al 75 aniversario de la Fundación de la March of Dimes. Felicito a la Fundación por sus años de dedicación y por sus servicios para mejorar la vida de las mujeres, los bebés y los niños”, dijo Ríos.
“Fue muy interesante ver cómo se hacen las monedas”, dijo Aidan, que fue Embajador Nacional de la March of Dimes en 2014 y cuyo abuelo fue un “pionero de la polio”, uno de los niños que participaron en la enorme prueba en el terreno para probar la vacuna de Salk contra la polio en 1954. Aidan planea estar entre los primeros en ordenar monedas y las dará como regalos a las enfermeras que lo cuidaron cuando estaba recién nacido.
El nacimiento prematuro es la principal causa de muerte entre los recién nacidos en los Estados Unidos. En todo el mundo, más de un millón de niños muere cada año debido a complicaciones del nacimiento prematuro. Los bebés que sobreviven al nacimiento prematuro con frecuencia afrontan problemas de salud toda la vida, como problemas de la vista y de la respiración, parálisis cerebral y deficiencias del aprendizaje.
La ley de la moneda conmemorativa de la March of Dimes fue auspiciada en el Congreso por la ex senadora Kay Hagan (demócrata por Carolina del Norte), la senadora Susan Collins (republicana por Maine), el representante Bob Dold (republicano por Illinois) y la representante Nita Lowey (demócrata por Nueva York). El presidente Barack Obama firmó la ley en 2012 autorizando la producción hasta de 500,000 dólares de plata conmemorando el 75 aniversario de la March of Dimes y celebrando “su distinguido historial de generar el apoyo de los norteamericanos para proteger la salud de nuestros niños”.

Los precios iniciales de $46.95 (prueba) y $43.95 (sin circular) son válidos hasta las 3:00 p.m. del 13 de abril de 2015. Se autoriza pagar a la March of Dimes sobretasas de $10 por cada dólar de plata vendido para financiar las investigaciones, la educación y los servicios dirigidos a mejorar la salud de las mujeres, los bebés y los niños. El público puede comprar monedas en http://1.usa.gov/1MoGVwF.
La March of Dimes es la principal organización sin fines de lucro para la salud en el embarazo y del bebé. Durante más de 75 años, las madres y los bebés se han beneficiado de las investigaciones, la educación, las vacunas y los adelantos de la March of Dimes. Averigüe cómo puede ayudar a recaudar fondos para prevenir el nacimiento prematuro y los defectos congénitos caminando en la Marcha por los Bebés en marchforbabies.org. Búsquenos en Facebook y síganos en Twitter.
La Marcha por los Bebés es patrocinada nacionalmente por el principal donante corporativo de la March of Dimes, Kmart, y por los importantes socios Famous Footwear, Macy’s, Cigna, United Airlines y Mission Pharmacal.
FUENTE March of Dimes Leer más: Moneda de la March of Dimes celebra la derrota de la polio y la misión actual sobre la salud de los bebes http://www.bolsamania.com/noticias-actualidad/notasDePrensa/Moneda-de-la-March-of-Dimes-celebra-la-derrota-de-la-polio-y-la-mision-actual-sobre-la-salud-de-los–ES52190–18a36ceeb2e4593a62369c272554cbdb.html#QlS0P94iWRsvdI3H

 

Publicado en Lo qué te intereza saber, Noticias y política, Polio, Salud, Poliomielitis, Síndrome de Post Polio(SPP) y Más | Etiquetado | Deja un comentario

CRANIOSACRAL THERAPY, HEALTHY TIPS, PAINPAIN MANAGEMENT.

POSTED OCTOBER 16TH, 2013

Craniosacral Therapy
By Donald Levy, MD
Medical Director, Osher Clinical Center

CraniosacralTherapy

 

There is a lot of misunderstanding and confusion over many treatments and health related professions that fall outside of mainstream medical care. We would like to dedicate some space in this, and future, issues of Healthy 850 to present and explain some therapies that are considered “Complementary” or “Alternative.” This month, we begin with “Craniosacral Therapy.”
What is “Craniosacral Therapy”

Craniosacral Therapy (CST) is a method of evaluating and enhancing the function of a physiological body system called by its practitioners the craniosacral system. The goal of this gentle, hands-on method is to encourage the release and relaxation of membranous and musculoskeletal connective tissues surrounding the central nervous system and throughout the body that are potential causes of sensory, motor or neurological disability. It was developed by John E. Upledger, in the late 1970’s and has been used in the management of a variety of problems including migraines, chronic head neck and back pain, TMJ syndrome, fibromyalgia, emotional and stress-related disorders, chronic fatigue and even multiple sclerosis.

Craniosacral Therapy

In our clinic, we have seen positive responses with this modality and there are almost no reports of adverse effects. However, as with a number of modalities that might be loosely classified as forms of “energy medicine”, there is skepticism from some in the scientific community about this therapy because it does not seem biologically plausible according to our current understanding of basic anatomy and physiology. As we wait for better research on the underlying concepts, we can say that there are some early clinical outcome studies suggesting that, whatever the exact mechanism, craniosacral therapy can be effective. For example:

– Arnadottir TS, Sigurdarottir AK. Is craniosacral therapy effective for migraine? Tested with HIT-6 questionnaire. Complement Ther Clin Pract. 2013;19(1):11-4
– Jakel A, vonHauenschild P. A systematic review to evaluate the clinical benefits of craniosacral therapy. Complement Ther Med. 2012;20(6):456-65
– Harrison RE, Page JS. Multipractitioner Upledger craniosacral therapy: descriptive outcome study 2007-2008. J Altern Complement Med. 2011;17(1):13-7
– Raviv G et. al. Effect of craniosacral therapy on lower urinary tract signs and symptoms in multiple sclerosis. Complement Ther Clin Pract. 2009;15(2):72-5
A typical Craniosacral therapy session takes place in a quiet, private room. Patients lie on a comfortable, padded table in a relaxed position and remain fully clothed. The best practitioners of this gentle touch therapy have completed many hours of instruction and training and often practice this modality exclusively.
Publicado en Lo qué te intereza saber, Salud, Poliomielitis, Síndrome de Post Polio(SPP) y Más | Etiquetado | Deja un comentario

Why the Next Outbreak Could Be Polio

Measles is breaking out in California, Illinois, New Jersey and surely more to come. Is Polio next?

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By Bethany Mandel | 02/06/15 10:22am
Dr. Jeffrey Gunzenhauser, Interim Health Officer from the Los Angeles County Department of Public Health, briefs the media outside the Department of Public Health in Los Angeles, California on February 4, 2015, with a general update of the measles outbreak in Los Angeles County.
Dr. Jeffrey Gunzenhauser, Interim Health Officer from the Los Angeles County Department of Public Health, briefs the media outside the Department of Public Health in Los Angeles, California on February 4, 2015, with a general update of the measles outbreak in Los Angeles County. (Photo: Frederic J. Brown/Getty Images)

With news of the latest measles outbreak, this time originating in Disneyland, I found myself somewhat relieved that at the very least, we weren’t seeing a resurgence of polio. Finally, after dozens of outbreaks of diseases once relegated to the Oregon Trail, Americans have taken notice of the danger posed by the anti-vaccine movement and its adherents. They are your friends, they might even be your family. But they are putting the lives of all of our children, not least their own, at risk.

In the year 2000, the measles disease was eliminated from the United States. We had taken a major step forward in the field of public health. In came Jenny McCarthy and her false belief that the MMR shot caused her son’s autism (which, in the end, wasn’t even autism), and we took a big step right back. Polio, like the measles, is a disease still present in the rest of the world, but largely forgotten here in the U.S. There are Americans who still remember it; just ask Senate Majority Leader Mitch McConnell, who survived a bout of it when he was 2 years old. We’ve come close to eliminating it worldwide, thanks to the decades-long work of Rotary International, but we haven’t quite gotten there yet. World events keep getting in the way. Vaccination workers are killed by terrorists, vaccination drives interrupted by war, highland villages are isolated by mudslides. There are, thus, tragically still cases of polio emerging even in the year 2015.

As we saw when Ebola arrived on our soil, we live in an ever-shrinking world. What is a problem for Nigeria or Pakistan can become ours with one short international flight. As much as international health professionals do wonderful work, they also are afflicted with the same God complex that doctors here possess, and break quarantine rules designed to protect the rest of us because they think they know better. We saw it with a doctor who went bowling in Brooklyn and a CNN correspondent who deemed takeout soup more important than the health of the occupants of the restaurant she walked into to pick it up. Between patients and the doctors who treat them, the distance between a remote village in Pakistan and our nation’s shores isn’t very far.

During a recent outbreak of the measles in New York City ultra-Orthodox enclaves of Brooklyn were hard hit due to anti-vaccine sentiment (which holds no basis in Judaism) within the community

One doesn’t even have to go so far as the highlands of Pakistan to find polio. Recently the virus was discovered in the groundwater in Israel. Thanks to the upheaval neighboring Syria experienced during their civil war, the virus made an appearance there. During a recent outbreak of the measles in New York City’s ultra-Orthodox enclaves of Brooklyn were hard hit due to anti-vaccine sentiment (which holds no basis in Judaism) within the community. Imagine an individual contracting the disease in Israel (which had been conducting emergency vaccination clinics) and landing in the middle of the unvaccinated capital of Hasidic Judaism in Boro Park, with a stopover perhaps in the Land of Kale: Park Slope. The scenario, entirely plausible, is every epidemiologist’s worst nightmare.

This being America, the vaccination issue has become political. Several politicians, including New Jersey Governor Chris Christie, have indicated that while families should vaccinate, they should be able to choose what is best for their children. NBC reported on his remarks:

Pressed by reporters about whether he believes vaccines are dangerous, Mr. Christie responded: “I didn’t say that – I said different disease types can be more lethal so that the concern would be measuring whatever the perceived danger is by a vaccine and we’ve had plenty of that over a period of time versus what the risk to public health is. And that’s exactly what I mean by what I said.”

To be clear, there is no proven danger to any vaccine currently on the market, and every vaccine prevents a lethal and dangerous disease.

What goes through the mind of anti-vaccine parents? Some refuse all vaccines, others pick and choose, as Mr. Christie suggested they could and should. How does a parent educated by Google University choose a schedule better than their pediatricians, medical associations, and epidemiologists? In my mind the debate goes something like this:

“Diphtheria? I’m not even sure what that is, but that one sounds serious. Yes, let’s do that.” “Polio? That hasn’t been around since my grandparents’ time! Who ever heard of anyone getting polio these days? That’s one we can definitely skip.”

With search engines and now, unfortunately, politicians telling parents they can pick and choose vaccines, the fear should be that the polio shot will be dropped by the wayside even more than it already has. If so, the next outbreak we see will be far more serious than measles. Soon, we will be referencing blueprints from the 1950s to build iron lungs for not only their children, but also our own, who might be too young or immunocompromised to receive the vaccine themselves.

Read more at http://observer.com/2015/02/why-the-next-outbreak-could-be-polio/#ixzz3RHXA0hNj

Publicado en Noticias y política, Salud, Poliomielitis, Síndrome de Post Polio(SPP) y Más | Deja un comentario

What must Pakistan do to beat polio?

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M Ilyas Khan
By M Ilyas Khan
BBC News, Islamabad
Pakistani polio vaccination worker Sher Khan (C) administers polio vaccine to a child in a poor neighbourhood that hosts Afghan refugees and internally displaced tribal people on the outskirts of Islamabad on December 29, 2014
Polio health workers are hoping this year will be better than past ones.

In recent years the Taliban have banned vaccinations in areas under their control, while scores of health workers or policemen guarding vaccine campaigns have been shot dead by gunmen.It was one of the reasons that in 2014 the country broke its own dubious record of reporting the highest number of cases in a single year for more than a decade – 303, as compared to the previous high of 199 in 2000.

In June 2014, the World Health Organization (WHO) recommended that all international travellers from Pakistan be administered polio drops at airports so as to prevent the proliferation of polio virus.

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An October editorial in the Dawn newspaper described this situation as Pakistan’s “badge of shame”.

Officials responsible for the country’s polio eradication efforts feel things have changed in recent years. More areas have become accessible to vaccination teams, and the government has been showing added interest in tackling the virus.

A member of the Pakistani security services stands guard while a health worker administers a polio vaccine to a child, in Peshawar, Pakistan, 20 December 2014
A member of the Pakistani security services stands guard during a polio vaccination in Peshawar
But no one is willing just yet to put a time frame on when Pakistan can be declared polio free.

The global initiative to eradicate the disease started in 1988 – the year Pakistan reported around 2,000 cases.

The country was then dealing with polio as part of its so-called “expanded programme on immunisation” (EPI), which was designed to eradicate six different vaccine-controllable diseases.

Taliban violence
In 1994, officials organised routine campaigns to administer oral poliovirus vaccine (OPV) to children.

There have been questions over the extent of coverage, with suggestions that only between 55% and 85% of children under five years of age had been vaccinated.

“But it did bring the incidence of polio down rather dramatically during the years leading up to 2000,” said Ashfaq Yusufzai, Peshawar-based health correspondent for Dawn newspaper.

In 2005, Pakistan recorded only 28 cases – its lowest number ever. But it was also the year a sometimes violent campaign of opposition to polio vaccination started in Swat, a region in the country’s north-west which at the time was being taken over by Taliban militants.

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Photo taken on November 26, 2008, shows Pakistani Taliban commander Latif Mehsud (C), a close aide to the former chief of the Tehreek-e-Taliban Pakistan (TTP), Hakimullah Mehsud, in Mamouzai area of the Orakzai Agency
Taliban militants opposed polio vaccinations in Pakistan
“Since then, Pakistan’s polio eradication effort has been largely held hostage by militants, and flaws in its administrative arrangements have become more glaring,” said Ashfaq Yusufzai.

Besides, a constant tug-of-war between the country’s civilian and military leadership has prevented civilian governments, at the helm since 2008, from focusing on polio and evolving better eradication strategies.

Parental refusals and occasional manhandling of health workers started in 2005, and became violent after the May 2011 killing of Osama Bin Laden – especially after the ISI intelligence agency accused a doctor, Shakil Afridi, of conducting a “fake” vaccination campaign to help the Americans track down the al-Qaeda chief.

Since then more than 60 health workers or policemen guarding vaccination campaigns have been shot dead by gunmen in the north-west and in the southern city of Karachi, where many people from the north-west live as economic migrants.

In June 2012, the Taliban banned polio vaccination drives in areas under their rule, thereby blocking vaccination of a significant chunk of the population they controlled in the north-western Khyber Pakhtunkhwa province and the adjoining Federally Administered Tribal Areas (Fata).

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People attend the funeral ceremony of polio health worker Muhammad Sarfarazin Faisalabad, Pakistan, 10 December 2014
The funeral of polio health worker Muhammad Sarfaraz in Faisalabad, December 2014
Officials cite this, and the killings of health workers, as the major reasons for the relapse in anti-polio efforts the country suffered in 2014.

But there have been other reasons as well, points out Dr Iqbal Memon, a member of the provincial polio eradication committee in Sindh province, of which Karachi is the capital.

“There has been no accountability, and so various players (the federal task force, the provincial health authorities, WHO and Unicef) have been accusing each other of failures,” he said.

In addition, he added, there have been problems maintaining the cold chain of the OPV – or a temperature-controlled supply line – while field officers have been reluctant to discard bad vaccine in a bid to manipulate their coverage figures.

Change for the better
The motivation level of health workers got a hit not only because of assassinations but also because the responsible officials failed to pay their fees on time, he says.

But many say there have been indications over the last few months that things are changing for the better.

Perhaps the most significant move has come from the military, which started an operation in the Waziristan region to clean up the Taliban’s major sanctuary on Pakistani territory.

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Pakistani soldiers stand near the debris of a house which was destroyed during a military operation against Taliban militants in the town of Miranshah in North Waziristan in this July 9, 2014
Pakistani army assaults against the Taliban have improved conditions for vaccination workers
Vaccinations in areas adjoining this region have picked up in recent weeks, and there have also been attempts to treat children displaced from the area.

Meanwhile the government has set up new “emergency polio cells” to improve security and access for health workers. The army and police have been made members of these cells in addition to health officials, the WHO and Unicef.

In an ideal world – where all of the population is accessible, vaccinators are not cheating on numbers, a perfect cold chain is maintained and at least 90% of the 40 million or so children are inoculated repeatedly during five to six monthly campaigns – Pakistan can eradicate polio in half a year, says Dr Imtiaz Ali Shah, the chief minister’s focal person on polio in the province of Khyber Pakhtunkhwa.

But there’s a technical hitch. “Most of our infected children are zero-dose – children who have never had OPV drops before,” he says.

“When we are able to restrict the incidence of polio to only those children who’ve had multiple doses of OPV and were infected only due to low immunity, we can then say that we are close to victory.”

Publicado en Polio, Salud, Poliomielitis, Síndrome de Post Polio(SPP) y Más | Etiquetado , , , , | Deja un comentario

El Dr. Henry escribe más sobre Post Polio “Fatiga cerebral”.

He escrito en el pasado sobre la fatiga post-polio cerebral. Este complejo de síntomas que experimentan muchos de nosotros implica un sentimiento de fatiga del cuerpo total, alerta restantes dificultad, encontrar problemas, dificultades de concentración y olvido ocasional. Estos problemas son generalmente ausente cuando nos estamos descansados. En la edición de noviembre-diciembre del Boletín del grupo de apoyo post poliomielitis Florida East Coast, hay un artículo escrito por Donald Peck Leslie, MD, del centro Shepherd, Inc. de Atlanta, Georgia titulado

FATIGA POST-POLIO: ¿QUÉ ES?

¿QUÉ PODEMOS HACER SOBRE ESO.”

Es un extenso artículo que resume el desarrollo del SPP y muchas de las teorías sobre las causas del SPP. Estaba particularmente interesado en algunas de las informaciones relativas a la fatiga del cerebral SPP e intentará lo relacionan con usted.

Citando el artículo del Dr. Leslie,

La fatiga es el más comúnmente divulgada y la más debilitantes de las secuelas  de post poliomielitis que afecta a los sobrevivientes de la polio en  Norteamérica hay  casi 2 millones y los menos estudiados. Entre los sobrevivientes de la polio en mi práctica, más 90% Informe nueva o aumentada de la fatiga. De estos, fatiga Informe aproximadamente la mitad que está interfiriendo significativamente con realizar o completar su trabajo. Hasta una cuarta parte de ellos tienen fatiga que interfiere con sus actividades de autocuidado. Otra literatura apoya estos porcentajes y es muy similar. Fatiga ha divulgado para ser provocado o aumentado por el esfuerzo físico en otra vez superior al 90% y por una cierta tensión emocional en más del 60%. Es importante que sobrevivientes de la polio distinguen entre cansancio físico y la resistencia disminuida asocian con nueva debilidad muscular, y lo que se llama  Se caracteriza por problemas con la atención y el pensamiento. Entre 70% y 95% de los sobrevivientes de la polio informaron fatiga , se quejaron de problemas de concentración, memoria, atención, palabra encontrando, mantener la vigilia y pensar con claridad.

El artículo del Dr. Leslie continúa

Problemas con la atención, la memoria y el pensamiento sugieren que los síntomas de la fatiga post-polio no pueden explicarse sólo por el virus de la polio dañan las células del cuerno anterior de las neuronas motoras de la médula espinal. Las autopsias que se realizaron en personas que murieron después de que la poliomielitis, si ellos estaban paralizados o no, mostraron que el virus de la polio hace 50 años casi siempre dañaron áreas específicas del cerebro, así como en la médula espinal. Hubo lesiones severas en la formación reticular, núcleos vestibulares, núcleos de techo de cerebelo y gris periacueductal. Las lesiones moderadas fueron vistas en el núcleo hipotalámico paraventricular, núcleo hipotalámico posterior y el  sustancia negra. Lesiones leves fueron encontrados en el globus pallidus y putamen, locus ceruleus, núcleos del rafe medio, núcleos hipotalámicos preópticas y núcleos talámico.

Como puede comprobar, el virus de la poliomielitis participan más del cerebro que la mayoría de nosotros habría conocido. Estas áreas dañadas incluyen sistema de activación del cerebro que nos ayuda a permanecer despierto y centrar nuestra atención. El virus también dañan las células nerviosas que producen neurotransmisores como la endorfinas(nuestra propia fuente de morfina), serotonina, dopamina y ACTH (corticotropina). El Dr. Leslie menciona que informes durante las epidemias de la poliomielitis gran cantidad indicaban que muchos pacientes experimentan somnolencia, letargo y hasta coma. Aproximadamente un tercio de los pacientes con poliomielitis espinal, bulbar y aun no-paralítica tenía desorientación, apatía y prolongado sueño.

He oído la información presentada por el Dr. Richard Bruno cuando informó a la Academia de Ciencias de Nueva York y también fue publicado en los archivos de medicina física y rehabilitación en 1993, un artículo titulado, “Neuropsicología de la fatiga post-polio.” Estos resultados indican la fatiga en el síndrome de fatiga crónica así como sobrevivientes de la polio se asocia con deterioro de la atención y velocidad de procesamiento de información, pero no de la memoria o capacidad de pensamiento. Teniendo en cuenta los resultados de lesiones graves y frecuentes de la polio virus en el sistema de activación del cerebro, fue presumido que el daño al sistema de activación del cerebro es probablemente responsable de fatiga y atención deteriorada en sobrevivientes de la polio.

Tratando de encontrar pruebas sobre esta hipótesis, MRI (imagen por resonancia magnética) realizado en algunos sobrevivientes de la polio con síntomas de fatiga cerebral. En un estudio divulgado en los archivos de medicina física y rehabilitación en 1994 titulado “La neuroanatomía de la fatiga post-polio,” manchas blancas fueron vistos en el sistema de activación del cerebro en la mayoría de los pacientes SPP con fatiga cerebral .

Me doy cuenta que gran parte de este artículo es técnico en la naturaleza, pero los datos indican que la investigación se está realizando para ayudar a explicar lo que está pasando a muchos de nosotros, y espero que finalmente resultará mejor tratamiento.

Publicado en Post Polio | Etiquetado , , , , , | Deja un comentario

Remembering Jonas Salk

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The Salk Institute name is inscribed in the steps leading to the heart of the research institute in La Jolla. Jonas Salk, the eponymous founder of the institute, discovered and developed the first successful inactivated polio vaccine.

The Salk Institute name is inscribed in the steps leading to the heart of the research institute in La Jolla. Jonas Salk, the eponymous founder of the institute, discovered and developed the first successful inactivated polio vaccine. — Howard Lipin

Polio, one of the most feared infectious diseases in the 20th century, was sent on the road to extinction by Dr. Jonas Salk, whose 100th birthday took place Oct. 28.

Three men who knew him well — Dr. Peter Salk, a son; Dr. Charles Cochrane of The Scripps Research Institute, and Dr. Geoffrey Wahl of the Salk Institute — told an audience of hundreds about Salk’s life work, legacy, and challenge for the future Friday evening. The event was moderated by my science guru colleague, Gary Robbins, who wrote an extensive and beautiful tribute to the man.

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Celebrating Jonas Salk’s ‘big life’

(On Thursday, Nov. 13, the Salk Institute will hold a symposium on viruses, vaccines and pandemics as part of its ongoing celebration of Salk’s centenary.

Polio is close to eradication. It now occurs in just three countries, Pakistan, Afghanistan and Nigeria. In March of this year, India was declared polio-free by the World Health Organization. No case of polio has been reported in India for three years. A decade ago, polio was also found in Niger, Egypt and India. The last case of polio was reported in the Americas, in Peru, in 1991.

Return of polio?

If polio isn’t eliminated everywhere, there’s always the chance that it could come back and spread, especially to populations that haven’t been vaccinated, Salk and Cochrane said at the event. That includes the United States, Cochrane said.

Below are some other video clips from the event, discussing various aspects of Salk’s life, challenges, the polio vaccine, and legacy.

Nonstop-Salk

Related Videos.

Salk the Insomniac

Encounter with Albert Sabin

Effectiveness of Salk Vaccine

Polio Boulevard — Too Late

Salk-institute-symbolism

Dimes no longer enough

He would be pleased

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